Essential Principles - LECTURES 1& 2

Introduction and General Overview:  Terms, Naming, Pharmacodynamics, Pharmacokinetics, socioeconomic, genetic, gender and age-dependent variables, etc.  Review of basic principles.

CLICK THE PHOTO TO DOWNLOAD THE Introductory Lecture Handout, Version April 2017, 1.4 MB, 21 pages

CLICK THE PHOTO TO DOWNLOAD THE Introductory Lecture Handout, Version April 2017, 1.4 MB, 21 pages

INTRODUCTORY LECTURE HANDOUT

This handout covers chapters 1 and 2 in the textbook and includes important general terms and surveys of pharmacodynamics (PD) and pharmacodynamics.

Click the photo of Atropa belladonna above to download the handout.

(The most updated .doc files for lectures will always be available to students through Oakton's D2L website)

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PHARMACODYNAMICS

Videos and handouts to help you master pharmacodynamics, the study of the mechanism of actions of drugs.

Introduction to Pharmacodynamics: Agonists, Antagonists and Receptors The handout is at: http://tinyurl.com/pw6wjzq Objectives: 1. Explain the ways an enzyme-substrate complex is the same as a receptor-ligand complex. 2. Explain the differences between an enzyme-substrate complex and a receptor-ligand complex. 3. Define the terms: site of action, receptor, ligand, enzyme, substrate, agonist, antagonist, direct-acting 4.
So agonists and antagonists actually only bind a subset of the receptors the natural ligand binds?! Confusing? Sure is! This video is meant to help you understand how receptor selectivity is related to the organ or system specificity of any given drug.
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PHARMACOKINETICS

Videos to help you master pharmacokinetics; that is not an easy task!!

REVIEW ACID-BASE

Short review of acids vs bases, pH, ionization, weak vs. strong acids, pKa and how all of these things relate to absorption of drugs through the stomach wall. For my Intro to Pharm students, who are predominantly pre-nursing and first-year nursing students. Go to http://www.boyev.com to get the "First Lecture" handout with the notes for this video.

REINFORCE:  FIRST PASS METABOLISM

A bit more discussion about first-pass metabolism ("first pass effect")to hopefully clarify things a bit. Objectives: 1. Explain what "metabolism" means in the field of pharmacology and pharmacokinetics. 2. Explain how the "first pass effect" affects bioavailability and dosing for drugs given via an enteral route. 3.

Lecture - week 2 - pharmacokinetics absorption and distribution

Quick and dirty recording of Week 2 Lecture Bio244 Dr. Boyev Recorded Jan 27 2016

LECTURE - WEEK 2 - Pharmacokinetics:  Metabolism and Excretion